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Literature summary for 3.4.21.106 extracted from

  • Tsuji, A.; Torres-Rosado, A.; Arai, T.; Le Beau, M.M.; Lemons, R.S.; Chou, S.H.; Kurachi, K.
    Hepsin, a cell membrane-associated protease. Characterization, tissue distribution, and gene localization (1991), J. Biol. Chem., 266, 16948-16953.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
plasma membrane
-
Homo sapiens 5886
-
plasma membrane
-
Papio ursinus 5886
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
44000
-
SDS-PAGE, enzyme after cell-free translation assay Homo sapiens
51000
-
mature protein, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Protein + H2O Homo sapiens
-
?
-
?
Protein + H2O Papio ursinus
-
?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Papio ursinus
-
young adult baboon
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein larger size of enzyme in cell extracts as compared to cell-free translation assay may be due to glycosylation, possible site for N-linked carbohydrate chain attachment is at amino acid 112 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
adrenal gland low level Papio ursinus
-
kidney
-
Papio ursinus
-
liver
-
Homo sapiens
-
liver highest level Papio ursinus
-
lung
-
Papio ursinus
-
additional information enzyme is present in most tissues, highest level in liver Homo sapiens
-
pancreas
-
Papio ursinus
-
pituitary gland
-
Papio ursinus
-
small intestine low level Papio ursinus
-
spleen low level Papio ursinus
-
testis
-
Papio ursinus
-
thymus low level Papio ursinus
-
thyroid gland
-
Papio ursinus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Protein + H2O
-
Homo sapiens ?
-
?
Protein + H2O
-
Papio ursinus ?
-
?