Literature summary for 3.4.17.10 extracted from

Murthy, S.R.; Thouennon, E.; Li, W.S.; Cheng, Y.; Bhupatkar, J.; Cawley, N.X.; Lane, M.; Merchenthaler, I.; Loh, Y.P.
Carboxypeptidase E protects hippocampal neurons during stress in male mice by up-regulating prosurvival BCL2 protein expression (2013), Endocrinology, 154, 3284-3293.

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Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
hippocampus	after mild chronic restraint stress, CPE protein and mRNA are significantly elevated in the hippocampal CA3 region, compared to naive littermate	Mus musculus	-

Synonyms

Synonyms	Comment	Organism
carboxypeptidase E	-	Mus musculus

Expression

Organism	Comment	Expression
Mus musculus	after mild chronic restraint stress, CPE protein and mRNA are significantly elevated in the hippocampal CA3 region, compared to naïve littermate	up

General Information

General Information	Comment	Organism
physiological function	CPE can mediate neuroprotection of the hippocampal neurons during mild chronic restraint stress and may play an important role in maintaining allostasis	Mus musculus

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Release 2023.1 (January 2023)