Cloned (Comment) | Organism |
---|---|
ACE insertion/deletion genotyping | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
additional information | ACE insertion/deletion and bradykinin B2 receptor polymorphisms are not involved in the development of ACEi-induced angio-oedema, ACE insertion/deletion polymorphism identification and analysis, overview | Homo sapiens |
additional information | polymorphism of ACE insertion/deletion, e.g. cC181T, and the bradykinin B2 receptor polymorphisms are not involved in the development of ACEi-induced angioedema, overview | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
angiotensin-converting enzyme inhibitor | ACEi, induces angioedema, a non-allergic bradykinin-induced drug side-effect and clinical life-threatening problem, overview. ACE insertion/deletion and bradykinin B2 receptor polymorphisms are not involved in the development of ACEi-induced angio-oedema | Homo sapiens | |
additional information | ACE inhibitors can induce angioedema, overview; ACE-inhibitors in vivo act in a competitive manner and their activity is dependent on their plasma concentration | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
bradykinin + H2O | Homo sapiens | degradation | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood serum | - |
Homo sapiens | - |
serum | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
ACE activities in serum from angioedema patients, overview | Homo sapiens |
additional information | - |
ACE I/D polymorphism in relation to ACE serum activity, serum activity in U/l, overview | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
bradykinin + H2O | - |
Homo sapiens | ? | - |
? | |
bradykinin + H2O | degradation | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ACE | - |
Homo sapiens |
angiotensin-converting enzyme | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
malfunction | ACE inhibitors can induce angioedema, overview. Polymorphism of ACE insertion/deletion and the bradykinin B2 receptor polymorphisms are not involved in the development of ACEi-induced angioedema, overview | Homo sapiens |