Application | Comment | Organism |
---|---|---|
medicine | the review focuses mainly on the preclinical studies underlying the development DPP IV inhibitors appropriate for diabetes therapy and their proposed mode of action, and summarized the clinical experience to date | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ABT-279 | - |
Homo sapiens | |
ABT-341 | - |
Homo sapiens | |
alogliptin | - |
Homo sapiens | |
ALS 2-0426 | - |
Homo sapiens | |
BI 1356 | - |
Homo sapiens | |
denagliptin | - |
Homo sapiens | |
GRC8200 | - |
Homo sapiens | |
NVP DPP728 | - |
Homo sapiens | |
P32/98 | - |
Homo sapiens | |
PHX 1149 | - |
Homo sapiens | |
PSN-9301 | - |
Homo sapiens | |
R1438 | - |
Homo sapiens | |
saxagliptin | - |
Homo sapiens | |
sitagliptin | - |
Homo sapiens | |
SSR-162369 | - |
Homo sapiens | |
TA-6666 | - |
Homo sapiens | |
TS-021 | - |
Homo sapiens | |
vildagliptin | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | integral membrane protein | Homo sapiens | 16020 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | dipeptidyl peptidase IV is the major enzyme responsible for degrading the incretins in vivo | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | - |
Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | dipeptidyl peptidase IV is the major enzyme responsible for degrading the incretins in vivo | Homo sapiens | ? | - |
? |