Crystallization (Comment) | Organism |
---|---|
enzyme crystallizes as a linear homohexamer which is held together by electrostatic interactions and H-bonding, and each subunit binds one Zn2+. The active site if VanX is in a cavity of 150 A that can only accomodate small molecules which explains the narrow substrate specificity of the enzyme. The Zn2+ is coordinated in a destorted tetrahedral arrangement with the side chains of His116, His184, Asp123 and a solvent water | Enterococcus faecium |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
23400 | - |
- |
Enterococcus faecium |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Enterococcus faecium | - |
- |
- |
Subunits | Comment | Organism |
---|---|---|
dimer | exists as a dimer in solution but aggregates when at high concenctrations | Enterococcus faecium |
Synonyms | Comment | Organism |
---|---|---|
VanX | - |
Enterococcus faecium |