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Literature summary for 3.2.2.26 extracted from

  • Li, X.; Apel, D.; Gaynor, E.C.; Tanner, M.E.
    5'-methylthioadenosine nucleosidase is implicated in playing a key role in a modified futalosine pathway for menaquinone biosynthesis in Campylobacter jejuni (2011), J. Biol. Chem., 286, 19392-19398.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.2.2.26

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21(DE3) cells Campylobacter jejuni

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.00103
-
 6-amino-6-deoxyfutalosine at pH 7.0 and 25°C Campylobacter jejuni

Organism

Organism UniProt Comment Textmining
Campylobacter jejuni
-
-
-
Campylobacter jejuni NCTC 11168
-
-
-
Streptomyces coelicolor Q9KXN0
-
-
Thermus thermophilus Q5SKT7
-
-

Purification (Commentary)

Purification (Comment) Organism
Sepharose column chromatography Campylobacter jejuni

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6-amino-6-deoxyfutalosine + H2O
-
 Campylobacter jejuni dehypoxanthine futalosine + adenine
-
 ?
6-amino-6-deoxyfutalosine + H2O
-
 Campylobacter jejuni NCTC 11168 dehypoxanthine futalosine + adenine
-
 ?
futalosine + H2O
-
 Thermus thermophilus dehypoxanthine futalosine + hypoxanthine
-
 ?
futalosine + H2O
-
 Streptomyces coelicolor dehypoxanthine futalosine + hypoxanthine
-
 ?

Synonyms

Synonyms Comment Organism
5'-methylthioadenosine nucleosidase
-
 Campylobacter jejuni
futalosine nucleosidase
-
 Thermus thermophilus
futalosine nucleosidase
-
 Streptomyces coelicolor
MqnB
-
 Thermus thermophilus
MqnB
-
 Streptomyces coelicolor
MTAN
-
 Campylobacter jejuni

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.53
-
 6-amino-6-deoxyfutalosine at pH 7.0 and 25°C Campylobacter jejuni