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Literature summary for 3.2.2.23 extracted from
- Structural insight into the discrimination between 8-oxoguanine glycosidic conformers by DNA repair rnzymes A molecular dynamics study of human oxoguanine glycosylase 1 and formamidopyrimidine-DNA glycosylase (2018), Biochemistry, 57, 1144-1154 .
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
| FPG catalytic residues are suitably aligned for both 7,8-dihydro-8-oxoguanine syn- and anti-conformers, with anti-7,8-dihydro-8-oxoguanine forming a Watson-Crick pair with cytosine being more favorably bound. In the mechanism, sugar-ring opening may precede nucleoside deglycosylation | Geobacillus stearothermophilus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Geobacillus stearothermophilus | P84131 | - |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| MutM | - |
Geobacillus stearothermophilus |
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Release 2023.1 (January 2023)
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