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BRENDA support

Literature summary for 3.2.1.B28 extracted from

  • Voorhorst, W.G.B.; Gueguen, Y.; Geerling, A.C.M.; Schut, G.; Dahlke, I.; Thomm, M.; van der Oost, J.; de Vos, W.M.
    Transcriptional regulation in the hyperthermophilic archaeon Pyrococcus furiosus: coordinated expression of divergently oriented genes in response to beta-linked glucose polymers (1999), J. Bacteriol., 181, 3777-3783.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Pyrococcus furiosus Q51723
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Expression

Organism Comment Expression
Pyrococcus furiosus gene locus includes the celB gene, and a divergently orientated gene cluster, adhA-adhB-lamA, which codes for two alcohol dehydrogenases and an extracellular beta-1,3-endoglucanase. The in vivo and in vitro transcription initiation sites of both the celB gene and the lamA operon lie 25 nucleotides downstream of conserved TATA box motifs additional information
Pyrococcus furiosus during growth of Pyrococcus furiosus on either cellobiose or laminarin, the activities of both beta-glucosidase and endoglucanase are increased at least fivefold compared with levels during growth on maltose or pyruvate, due to an enhanced transcription of both the celB gene and the lamA operon in the presence of these glucose-containing substrates up