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BRENDA support

Literature summary for 3.2.1.76 extracted from

  • Clarke, L.A.; Wraith, J.E.; Beck, M.; Kolodny, E.H.; Pastores, G.M.; Muenzer, J.; Rapoport, D.M.; Berger, K.I.; Sidman, M.; Kakkis, E.D.; Cox, G.F.
    Long-term efficacy and safety of laronidase in the treatment of mucopolysaccharidosis I (2009), Pediatrics, 123, 229-240.
    View publication on PubMed

Application

Application Comment Organism
medicine long-term clinical benefit and safety of laronidase in attenuated patients with mucopolysaccharidosis I. Laronidase effectively treats respiratory dysfunction, poor endurance, restricted mobility, hepatomegaly, and decreased quality of life. Prompt disease recognition and early and sustained treatment with laronidase will maximize these important benefits of treatment Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Synonyms

Synonyms Comment Organism
alpha-L-iduronidase
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Homo sapiens
laronidase
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Homo sapiens