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Literature summary for 3.2.1.48 extracted from

  • Hauri, H.P.; Quaroni, A.; Isselbacher, K.J.
    Biogenesis of intestinal plasma membrane: posttranslational route and cleavage of sucrase-isomaltase (1979), Proc. Natl. Acad. Sci. USA, 76, 5183-5186.
    View publication on PubMedView publication on EuropePMC

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
140000
-
1 * 140000 - 160000 + 1 * 140000 -160000 2 large subunits, EC 3.2.1.48 and EC 3.2.1.10, functional dimer, SDS-PAGE Rattus rattus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
maltose + H2O Rattus rattus
-
2 glucose
-
?
sucrose + H2O Rattus rattus
-
D-glucose + D-fructose
-
?

Organism

Organism UniProt Comment Textmining
Rattus rattus
-
sucrase-isomaltase synthesized as a one-chain polypeptide, precursor that is split into the subunits after its transfer to the microvillus membrane
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
maltose + H2O
-
Rattus rattus 2 glucose
-
?
sucrose + H2O
-
Rattus rattus D-glucose + D-fructose
-
?

Subunits

Subunits Comment Organism
dimer 1 * 140000 - 160000 + 1 * 140000 -160000 2 large subunits, EC 3.2.1.48 and EC 3.2.1.10, functional dimer, SDS-PAGE Rattus rattus