Any feedback?
Literature summary for 3.1.4.37 extracted from
- Ethanol exerts different effects on myelin basic protein and 2',3'-cyclic nucleotide 3'-phosphodiesterase expression in differentiating CG-4 oligodendrocytes (2001), Brain Res. Dev. Brain Res., 128, 9-16.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | effect of ethanol on the activity and expression of CNP isoenzymes, ethanol does not alter the developmentally regulated increased expression of CNP isoenzymes or enzyme activity | Rattus norvegicus |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 46000 | - |
x * 46000, major CNP isoenzyme, x * 48000, minor CNP isoenzyme | Rattus norvegicus |
| 48000 | - |
x * 46000, major CNP isoenzyme, x * 48000, minor CNP isoenzyme | Rattus norvegicus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| nucleoside 2',3'-cyclic phosphate + H2O | Rattus norvegicus | plays a role in cytoskeletal rearrangement, cell morphology and cell process outgrowth, increased expression of CNP is a marker for oligodendrocyte development | nucleoside 2'-phosphate | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
2 isoenzymes of 46 and 48 kDa | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| oligodendrocyte | bipotential proliferating and differentiating CG-4 cells | Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 2',3'-cyclic NADP+ + H2O | - |
Rattus norvegicus | NADP+ | - |
? | |
| nucleoside 2',3'-cyclic phosphate + H2O | - |
Rattus norvegicus | nucleoside 2'-phosphate | - |
? | |
| nucleoside 2',3'-cyclic phosphate + H2O | plays a role in cytoskeletal rearrangement, cell morphology and cell process outgrowth, increased expression of CNP is a marker for oligodendrocyte development | Rattus norvegicus | nucleoside 2'-phosphate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 46000, major CNP isoenzyme, x * 48000, minor CNP isoenzyme | Rattus norvegicus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
