Cloned (Comment) | Organism |
---|---|
gene nuc1, recombinant expression in Escherichia coli strain BL21(DE3) | Staphylococcus aureus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Staphylococcus aureus | - |
gene nuc1 | - |
Staphylococcus aureus RN4220 | - |
gene nuc1 | - |
Synonyms | Comment | Organism |
---|---|---|
NUC1 | - |
Staphylococcus aureus |
staphylococcal nuclease | - |
Staphylococcus aureus |
General Information | Comment | Organism |
---|---|---|
malfunction | when the nuc1 gene is knocked out, the ability of Staphylococcus aureus strains to form a biofilm significantly increased | Staphylococcus aureus |
physiological function | staphylococcal nuclease is an important virulence factor of Staphylococcus aureus. Biofilm development can be prevented in staphylococcal nuclease-producing strains of Staphylococcus aureus, direct relationship between staphylococcal nuclease production and the prevention of biofilm development, overview. Staphylococcal nuclease affects biofilm formation by other bacteria, such as Pseudomonas aeruginosa and Staphylococcus epidermis. Only bacterial strains that do not possess the nuc1 gene are able to form biofilms | Staphylococcus aureus |