Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Triton X-100 | plasma membrane-associated activity is absolutely dependent on detergent | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
F- | - |
Homo sapiens | |
NEM | inhibition of cytosolic and light membrane activity | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.062 | - |
phosphatidic acid | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | 20% of the activity | Homo sapiens | 5829 | - |
additional information | the majority of the activity is localized in particulate fraction | Homo sapiens | - |
- |
plasma membrane | - |
Homo sapiens | 5886 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | moderate inhibition of cytosolic and particulate activity | Homo sapiens | |
Mg2+ | markedly potentiates the cytosolic but not the particulate activity | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
neutrophil | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
phosphatidic acid + H2O | - |
Homo sapiens | 1,2-diacyl-sn-glycerol + phosphate | - |
? |