Application | Comment | Organism |
---|---|---|
molecular biology | intersectin1 (ITSN1) is identified as a binding partner of the SH2 domain containing inositol 5-phosphatase 2 (SHIP2). In response to epidermal growth factor, SHIP2 expression is able to recruit the ITSN1 short form (ITSN1-S) to the cell membrane, while SHIP2 overexpression does not modulate the ITSN-mediated extracellular signal-regulated kinase1/2 and c-Jun NH2-terminal kinase activation | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
expressed in COS-7 cells and in Saccharomyces cerevisiae | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | intersectin1 (ITSN1) is identified as a new binding partner of the SH2 domain containing inositol 5-phosphatase 2 (SHIP2) | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | intersectin1 (ITSN1) is identified as a new binding partner of the SH2 domain containing inositol 5-phosphatase 2 (SHIP2) | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SH2 domain containing inositol 5-phosphatase 2 | - |
Homo sapiens |
SHIP2 | - |
Homo sapiens |