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Literature summary for 3.1.3.16 extracted from

  • Zhi, X.; Zhang, H.; He, C.; Wei, Y.; Bian, L.; Li, G.
    Serine/threonine protein phosphatase-5 accelerates cell growth and migration in human glioma (2015), Cell. Mol. Neurobiol., 35, 669-677 .
    View publication on PubMed
Search for more literature for 3.1.3.16

Protein Variants

Protein Variants Comment Organism
additional information short hairpin RNA targeting PPP5C gene is used to knockdown PP5 expression in human glioma cell lines U251 and U373, knockdown of PP5 mitigates glioma cell migration by lentivirus infection Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P53041
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-

Source Tissue

Source Tissue Comment Organism Textmining
glioma cell
-
 Homo sapiens
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U-251 cell
-
 Homo sapiens
-
U-373 cell
-
 Homo sapiens
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Synonyms

Synonyms Comment Organism
PP5
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 Homo sapiens
Ppp5
-
 Homo sapiens
Ppp5c
-
 Homo sapiens
Ser/Thr protein phosphatase 5
-
 Homo sapiens
serine/threonine protein phosphatase-5
-
 Homo sapiens

General Information

General Information Comment Organism
malfunction depletion of PPP5C via RNAi remarkably inhibits glioma cell proliferation and colony formation, and arrests cell cycle in the G0/G1 phase. Moreover, knockdown of PP5 markedly suppresses glioma cell migration Homo sapiens
physiological function role of enzyme PPP5C in glioma cell migration, overview. PPP5C is essential for glioma cell growth and serve as a promising therapeutic target in human gliomas Homo sapiens