Activating Compound | Comment | Organism | Structure |
---|---|---|---|
ceramide | ceramide induces increase of PP2A activity | Rattus norvegicus |
Application | Comment | Organism |
---|---|---|
medicine | PP2A inhibition may offer a new therapeutic approach to the treatment of diseases caused by cerebral ischemia | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
cantharidin | - |
Rattus norvegicus | |
okadaic acid | - |
Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
hippocampus | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
phosphorylated extracellular-signal-regulated kinase + H2O | PP2A is involved in the inactivation, but not the activation, of extracellular-signal-regulated kinase | Rattus norvegicus | extracellular-signal-regulated kinase + phosphate | - |
? | |
phosphorylated Raf + H2O | Raf is dephosphorylated at Ser259 | Rattus norvegicus | Raf + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PP2A | - |
Rattus norvegicus |
protein phosphatase 2A | - |
Rattus norvegicus |