Activating Compound | Comment | Organism | Structure |
---|---|---|---|
proliferating cell nuclear antigen | activity is enhanced by addition of Proliferating Cell Nuclear Antigen (PCNA) in vitro. The physical interaction between the two proteins through a PIP-motif of EndoQ and the toroidal structure of PCNA are critical for the stimulation of the endonuclease activity | Pyrococcus furiosus | |
proliferating cell nuclear antigen | activity is enhanced by addition of Proliferating Cell Nuclear Antigen (PCNA) in vitro. The physical interaction between the two proteins through a PIP-motif of EndoQ and the toroidal structure of PCNA are critical for the stimulation of the endonuclease activity | Thermococcus kodakarensis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pyrococcus furiosus | Q8U0N5 | - |
- |
Pyrococcus furiosus ATCC 43587 | Q8U0N5 | - |
- |
Thermococcus kodakarensis | Q5JI33 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
DNA + H2O | the enzyme recognizes uracil, abasic site and xanthine, as well as hypoxanthine, and cuts the phosphodiester bond at their 5' sides | Pyrococcus furiosus | ? | - |
? | |
DNA + H2O | the enzyme recognizes uracil, abasic site and xanthine, as well as hypoxanthine, and cuts the phosphodiester bond at their 5' sides | Thermococcus kodakarensis | ? | - |
? | |
DNA + H2O | the enzyme recognizes uracil, abasic site and xanthine, as well as hypoxanthine, and cuts the phosphodiester bond at their 5' sides | Pyrococcus furiosus ATCC 43587 | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
EndoQ | - |
Pyrococcus furiosus |
EndoQ | - |
Thermococcus kodakarensis |