Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Ap4A | - |
Homo sapiens | |
ATP | - |
Homo sapiens | |
ATPgammaS | - |
Homo sapiens | |
heparin | - |
Homo sapiens | |
additional information | no inhibition up to 40 mM by lysophosphatidylcholine | Homo sapiens | |
p-nitrophenyl-TMP | - |
Homo sapiens | |
pyridoxal 5'phosphate-6-azophenyl-2',4'-disulfonic acid | - |
Homo sapiens | |
RP-dATPalphaS | - |
Homo sapiens | |
SP-ATPalphaS | - |
Homo sapiens | |
SP-CTPalphaS | - |
Homo sapiens | |
SP-dATPalphaS | - |
Homo sapiens | |
UDP-glucose | - |
Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.016 | - |
[S]-d[T12] | - |
Homo sapiens | |
0.0715 | - |
[S]-d[A12] | - |
Homo sapiens | |
0.173 | - |
[RP-PS]-d[T12] | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
plasma | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | [RP-but last one-PS]-d[T12] is not hydrolyzed | Homo sapiens | ? | - |
? | |
[PO/Mix-PS]-d[TPOCPOTPOTPOTPOTPOTPSC] + H2O | 21% degraded after 2 hours, 35% degraded after 8 hours | Homo sapiens | ? | - |
? | |
[PO/Mix-PS]-d[TPOTPOTPOTPOTPOTPOTPOTPOTPOTPOTPST] + H2O | 35% degraded after 2 hours, 75% degraded after 8 hours | Homo sapiens | ? | - |
? | |
[PO/RP-PS]-d[TPOCPOTPOTPOTPOTPOTPSC] + H2O | 22% degraded after 2 hours, 45% degraded after 8 hours | Homo sapiens | ? | - |
? | |
[PO/SP-PS]-d[TPOCPOTPOTPOTPOTPOTPSC] + H2O | 20% degraded after 2 hours, 25% degraded after 8 hours | Homo sapiens | ? | - |
? | |
[PS]-d[A6] + H2O | - |
Homo sapiens | ? | - |
? | |
[RP-PS]-d[A12] + H2O | - |
Homo sapiens | ? | - |
? | |
[RP-PS]-d[T12] + H2O | 25% degraded after 2 hours, 75% degraded after 8 hours | Homo sapiens | ? | - |
? | |
[S]-d[A12] + H2O | - |
Homo sapiens | ? | - |
? | |
[S]-d[T12] + H2O | 100% degraded after 2 hours | Homo sapiens | ? | - |
? | |
[S]-d[TCCTCTTTTTTT] + H2O | - |
Homo sapiens | ? | - |
? | |
[S]-d[TCTTTTTC] + H2O | 100% degraded after 2 hours | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
3'-exonuclease | - |
Homo sapiens |
More | EC3.1.4.1/EC 3.6.1.9 | Homo sapiens |
NPP1 | - |
Homo sapiens |
nucleotide pyrophosphatase/phosphodiesterase 1 | - |
Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0002 | - |
inhibition of degradation of [RP-PS]-d[A12] | Homo sapiens | SP-ATPalphaS | |
0.0014 | - |
inhibition of degradation of [PO]-d[TCCTCTTTTTTT] | Homo sapiens | SP-ATPalphaS | |
0.0015 | - |
inhibition of degradation of [PO]-d[TCCTCTTTTTTT] | Homo sapiens | SP-dATPalphaS | |
0.002 | - |
inhibition of degradation of [PO]-d[A12] | Homo sapiens | SP-ATPalphaS | |
0.002 | - |
inhibition of degradation of [RP-PS]-d[A12] | Homo sapiens | RP-dATPalphaS | |
0.005 | - |
inhibition of degradation of [PO]-d[A12] | Homo sapiens | RP-dATPalphaS | |
0.005 | - |
inhibition of degradation of [PO]-d[TCCTCTTTTTTT] | Homo sapiens | RP-dATPalphaS | |
0.0084 | - |
inhibition of degradation of [PO]-d[TCCTCTTTTTTT] | Homo sapiens | SP-CTPalphaS | |
0.027 | - |
inhibition of degradation of [PO]-d[TCCTCTTTTTTT] | Homo sapiens | ATPgammaS | |
0.027 | - |
inhibition of degradation of [PO]-d[TCCTCTTTTTTT] | Homo sapiens | p-nitrophenyl-TMP | |
0.037 | - |
inhibition of degradation of [PO]-d[TCCTCTTTTTTT] | Homo sapiens | Ap4A | |
0.054 | - |
inhibition of degradation of [PO]-d[TCCTCTTTTTTT] | Homo sapiens | ATP | |
0.071 | - |
inhibition of degradation of [PO]-d[TCCTCTTTTTTT] | Homo sapiens | pyridoxal 5'phosphate-6-azophenyl-2',4'-disulfonic acid | |
0.106 | - |
inhibition of degradation of [PO]-d[TCCTCTTTTTTT] | Homo sapiens | UDP-glucose |