BRENDA - Enzyme Database show
show all sequences of 3.1.15.1

Alcohol esterification reactions and mechanisms of snake venom 5'-nucleotide phosphdiesterase

Garcia-Diaz, M.; Avalos, M.; Cameselle, J.C.; Eur. J. Biochem. 213, 1139-1148 (1993)

Data extracted from this reference:

Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Crotalus durissus terrificus
-
-
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
venom
-
Crotalus durissus terrificus
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
adenosine 5'-monophosphate-O-ethyl ester + H2O
-
134129
Crotalus durissus terrificus
adenosine 5'-monophosphate + ethanol
-
134129
Crotalus durissus terrificus
ir
adenosine 5'-triphosphate + 2,2-dichloroethanol
-
134129
Crotalus durissus terrificus
adenosine 5'-monophosphate-O-2,2-dichloroethyl ester + H2O + diphosphate
-
134129
Crotalus durissus terrificus
ir
adenosine 5'-triphosphate + 2-chloroethanol
-
134129
Crotalus durissus terrificus
adenosine 5'-monophosphate-O-2-chloroethyl ester + H2O + diphosphate
-
134129
Crotalus durissus terrificus
ir
adenosine 5'-triphosphate + ethylene glycol
-
134129
Crotalus durissus terrificus
adenosine 5'-monophosphate-O-ethylene glycolyl ester + H2O + diphosphate
-
134129
Crotalus durissus terrificus
ir
adenosine 5'-triphosphate + glycerol
-
134129
Crotalus durissus terrificus
adenosine 5'-monophosphate-O-glyceryl ester + H2O + diphosphate
-
134129
Crotalus durissus terrificus
ir
adenosine 5'-triphosphate + methanol
-
134129
Crotalus durissus terrificus
adenosine 5'-monophosphate-O-methyl ester + H2O + diphosphate
-
134129
Crotalus durissus terrificus
ir
adenosine 5'-triphosphate + propanol
-
134129
Crotalus durissus terrificus
adenosine 5'-monophosphate-O-propyl ester + H2O + diphosphate
-
134129
Crotalus durissus terrificus
ir
additional information
alcohol competes with water in esterification, so that adenosine 5'monophosphate can also be a product
134129
Crotalus durissus terrificus
?
-
-
-
-
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
venom
-
Crotalus durissus terrificus
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
adenosine 5'-monophosphate-O-ethyl ester + H2O
-
134129
Crotalus durissus terrificus
adenosine 5'-monophosphate + ethanol
-
134129
Crotalus durissus terrificus
ir
adenosine 5'-triphosphate + 2,2-dichloroethanol
-
134129
Crotalus durissus terrificus
adenosine 5'-monophosphate-O-2,2-dichloroethyl ester + H2O + diphosphate
-
134129
Crotalus durissus terrificus
ir
adenosine 5'-triphosphate + 2-chloroethanol
-
134129
Crotalus durissus terrificus
adenosine 5'-monophosphate-O-2-chloroethyl ester + H2O + diphosphate
-
134129
Crotalus durissus terrificus
ir
adenosine 5'-triphosphate + ethylene glycol
-
134129
Crotalus durissus terrificus
adenosine 5'-monophosphate-O-ethylene glycolyl ester + H2O + diphosphate
-
134129
Crotalus durissus terrificus
ir
adenosine 5'-triphosphate + glycerol
-
134129
Crotalus durissus terrificus
adenosine 5'-monophosphate-O-glyceryl ester + H2O + diphosphate
-
134129
Crotalus durissus terrificus
ir
adenosine 5'-triphosphate + methanol
-
134129
Crotalus durissus terrificus
adenosine 5'-monophosphate-O-methyl ester + H2O + diphosphate
-
134129
Crotalus durissus terrificus
ir
adenosine 5'-triphosphate + propanol
-
134129
Crotalus durissus terrificus
adenosine 5'-monophosphate-O-propyl ester + H2O + diphosphate
-
134129
Crotalus durissus terrificus
ir
additional information
alcohol competes with water in esterification, so that adenosine 5'monophosphate can also be a product
134129
Crotalus durissus terrificus
?
-
-
-
-
Other publictions for EC 3.1.15.1
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
729326
Trummal
Phosphodiesterase from Vipera ...
Macrovipera lebetina
Biochimie
106
48-55
2014
-
-
1
-
-
-
-
-
1
-
3
-
-
3
-
1
1
-
-
1
-
-
4
1
1
-
-
-
1
-
-
-
-
1
-
-
-
1
-
-
-
-
-
-
-
-
1
-
3
-
-
-
1
1
-
1
-
-
4
1
1
-
-
-
1
-
-
1
-
1
1
-
-
-
730323
Peng
Effects of metal ions and disu ...
Trimeresurus stejnegeri
Metallomics
5
920-927
2013
-
-
-
-
-
-
5
-
1
8
-
-
-
3
-
-
-
-
-
2
-
-
-
-
1
-
-
-
1
-
-
-
-
-
7
-
-
-
-
-
-
-
7
5
-
-
1
8
-
-
-
-
-
-
-
2
-
-
-
-
1
-
-
-
1
-
-
-
-
1
1
-
-
-
728951
Zhao
Capillary monolithic bioreacto ...
Crotalus atrox
Anal. Chem.
84
1157-1164
2012
1
1
-
-
1
1
-
-
1
-
-
1
-
2
-
-
-
-
-
3
-
-
2
-
1
-
-
-
1
-
-
-
-
-
-
1
1
-
-
-
1
1
-
-
-
-
1
-
-
1
-
-
-
-
-
3
-
-
2
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
716728
Al-Saleh
Purification and characterizat ...
Walterinnesia aegyptia
Prep. Biochem. Biotechnol.
41
262-277
2011
-
-
-
-
-
-
5
-
1
2
1
1
-
5
-
-
1
-
-
1
1
-
4
1
1
1
-
-
1
-
-
-
2
1
2
-
-
-
-
-
-
-
2
5
2
-
1
2
1
1
-
-
-
1
-
1
1
-
4
1
1
1
-
-
1
-
-
1
-
-
-
-
-
-
714122
Dhananjaya
An overview on nucleases (DNas ...
Trimeresurus stejnegeri
Biochemistry (Moscow)
75
1-6
2010
-
-
-
-
-
-
-
5
1
2
-
1
-
1
-
1
1
-
-
1
1
-
6
-
1
-
-
4
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
5
1
2
-
1
-
-
1
1
-
1
1
-
6
-
1
-
-
4
1
-
-
-
-
1
1
-
4
4
710182
Watts
Studies on the hydrolytic stab ...
Crotalus adamanteus
Org. Biomol. Chem.
7
1904-1910
2009
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
677528
Akamatsu
A novel methodology for charac ...
Crotalus adamanteus
Anal. Biochem.
362
229-235
2007
-
-
-
-
-
-
1
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
678280
Honcharenko
Comparison of the RNase H clea ...
Crotalus adamanteus
Biochemistry
46
5635-5646
2007
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
12
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
12
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
679157
Huo
Chemical constituents of plant ...
Crotalus adamanteus
Chem. Biodivers.
4
1-11
2007
-
1
-
-
-
-
4
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
4
-
1
-
-
-
-
-
4
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
678589
Choudhary
New biscoumarin derivatives-cy ...
Crotalus adamanteus
Bioorg. Med. Chem.
14
8066-8072
2006
-
-
-
-
-
-
26
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
24
-
27
-
-
-
-
-
-
-
27
26
24
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
679210
Hikishima
Synthesis and characterization ...
Crotalus adamanteus
Chembiochem
7
1970-1975
2006
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
680246
Akai
Helicobacter pylori induces mo ...
Crotalus adamanteus
Int. J. Oncol.
29
965-972
2006
-
-
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
682077
Mostafa
Phosphodiesterase-I inhibitor ...
Crotalus adamanteus
Nat. Prod. Res.
20
686-692
2006
-
-
-
-
-
-
3
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
668315
Aird
Taxonomic distribution and qua ...
Agkistrodon bilineatus, Agkistrodon piscivorus, Atropoides nummifer, Bitis arietans, Bitis gabonica, Bitis nasicornis, Bothriechis schlegelii, Bothrops alternatus, Bothrops asper, Bothrops atrox, Bothrops bilineatus, Bothrops cotiara, Bothrops jararaca, Bothrops jararacussu, Bothrops moojeni, Bothrops neuwiedi, Bothrops pradoi, Bungarus fasciatus, Calloselasma rhodostoma, Causus rhombeatus, Cerastes vipera, Crotalus adamanteus, Crotalus atrox, Crotalus basiliscus, Crotalus cerastes, Crotalus cerberus, Crotalus durissus, Crotalus horridus, Crotalus molossus, Crotalus oreganus concolor, Crotalus oreganus helleri, Crotalus oreganus lutosus, Crotalus oreganus oreganus, Crotalus ruber, Crotalus scutulatus, Crotalus viridis viridis, Daboia palaestinae, Daboia russelii, Deinagkistrodon acutus, Echis carinatus, Eristicophis macmahoni, Gloydius blomhoffii, Gloydius halys ussuriensis, Hypnale hypnale, Macrovipera lebetina, Montivipera xanthina, Naja atra, Naja haje, Naja kaouthia, Naja melanoleuca, Naja mossambica, Naja naja, Naja nigricollis, Naja nivea, Naja oxiana, Naja pallida, Naja sputatrix, Ophiophagus hannah, Porthidium lansbergii, Porthidium nasutum, Pseudocerastes persicus, Sistrurus miliarius barbouri, Sistrurus tergeminus, Vipera ammodytes, Vipera aspis, Vipera berus, Vipera latastei
Comp. Biochem. Physiol. B
140
109-126
2005
-
-
-
-
-
-
-
-
-
-
-
-
-
67
-
-
-
-
-
-
68
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
68
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
667920
Choudhary
Phenolic glyscosides, a new cl ...
Bothrops atrox
Bioorg. Med. Chem.
12
5793-5798
2004
-
-
-
-
-
-
2
-
-
-
-
-
-
4
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
2
-
2
-
-
-
-
-
-
-
2
2
2
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
653040
Valerio
Purification and characterizat ...
Bothrops alternatus
J. Protein Chem.
21
495-503
2002
-
-
-
-
-
1
5
1
-
1
1
-
-
1
-
-
1
-
-
-
-
3
1
1
1
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
1
-
5
-
1
-
1
1
-
-
-
-
1
-
-
-
3
1
1
1
-
1
-
1
-
-
-
-
-
-
-
-
-
653296
Fatima
Quinovic acid glycosides from ...
snake
Nat. Prod. Lett.
16
389-393
2002
-
-
-
-
-
-
4
-
-
-
-
-
-
4
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
134111
Tin-Win; Aye-Kyaw; Sanda; San-Aye; Win-Aung; Khin-Pa-Pa-Kyaw; Aung-Myat-Kyaw
-
Purification, characterization ...
Daboia siamensis
The Snake
28
83-89
1998
-
-
-
-
-
-
-
1
-
-
2
-
-
1
-
-
1
-
-
1
1
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
2
-
-
-
-
1
-
1
1
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
134128
Stoynov
Single-strand-specific DNase a ...
Crotalus adamanteus
FEBS Lett.
409
151-154
1997
-
-
-
-
-
-
1
-
-
-
1
-
-
3
-
-
-
-
-
2
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
2
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
134131
Vergeles
-
High efficiency of glycerol 2- ...
Crotalus durissus terrificus
Eur. J. Biochem.
223
442-447
1995
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
134129
Garcia-Diaz
Alcohol esterification reactio ...
Crotalus durissus terrificus
Eur. J. Biochem.
213
1139-1148
1993
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
2
-
-
8
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
8
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
134107
Kini
Rapid method for separation an ...
Protobothrops flavoviridis, Protobothrops flavoviridis Habu
J. Chromatogr.
291
299-305
1984
-
-
-
-
-
-
1
-
-
-
-
-
-
2
-
1
1
-
-
1
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
1
-
1
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
134108
Pollack
-
Snake venom phosphodiesterase: ...
Crotalus adamanteus
J. Protein Chem.
2
1-12
1983
-
-
-
-
-
-
6
-
-
1
-
-
-
1
-
-
1
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
6
-
-
-
1
-
-
-
-
-
1
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
134110
Dolapchiev
Venom exonuclease. III. Immuno ...
Crotalus adamanteus
Biochim. Biophys. Acta
667
355-360
1981
-
-
-
-
-
2
-
-
-
-
-
-
-
3
-
-
-
-
-
1
-
2
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
2
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
134109
Dolapchiev
Venom exonuclease. II. Amino a ...
Crotalus adamanteus
Biochim. Biophys. Acta
622
331-336
1980
-
-
-
-
-
-
-
-
-
3
-
-
-
3
-
2
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
2
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
134112
Dolapchiev
-
Venom exonuclease-kinetics and ...
Crotalus adamanteus
Int. J. Biol. Macromol.
2
7-12
1980
-
-
-
-
-
-
-
2
-
-
-
-
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
134133
Bugers
Hunneman, D.H.: Stereochemistr ...
Crotalus terrificus terrificus
J. Biol. Chem.
254
7476-7478
1979
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
134113
Oka
Snake venom phosphodiesterase: ...
Crotalus adamanteus, Crotalus atrox
Biochem. Biophys. Res. Commun.
80
841-848
1978
-
-
-
-
-
4
-
-
-
-
2
-
-
3
-
-
2
-
-
3
-
2
-
2
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
2
-
-
-
-
2
-
3
-
2
-
2
-
-
2
-
-
-
-
-
-
-
-
-
-
-
134114
Ballario
A simple method for the purifi ...
Vipera aspis
Anal. Biochem.
80
646-651
1977
-
-
-
-
-
-
-
1
-
2
1
-
-
1
-
-
1
-
-
1
1
1
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
2
1
-
-
-
-
1
-
1
1
1
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
134115
Philipps
Purification and characterizat ...
Bothrops atrox
Biochim. Biophys. Acta
432
237-244
1976
-
-
-
-
-
-
1
-
-
2
-
-
-
1
-
-
1
-
-
1
1
-
-
-
1
1
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
2
-
-
-
-
-
1
-
1
1
-
-
-
1
1
1
-
1
-
-
-
-
-
-
-
-
-
134116
Ogilvie
Affect of spleen and snake ven ...
Crotalus adamanteus
Biochem. Biophys. Res. Commun.
68
375-378
1976
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
134117
Philipps
Purification and characterizat ...
Crotalus adamanteus, Crotalus terrificus terrificus
Hoppe-Seyler's Z. Physiol. Chem.
356
1085-1096
1975
-
-
-
-
-
-
-
-
-
2
-
-
-
2
-
-
1
-
-
2
2
1
-
-
1
1
1
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
1
-
2
2
1
-
-
1
1
1
-
-
-
1
-
-
-
-
-
-
-
134119
Petrovaa
Partial degradation of transfe ...
Bothrops atrox, Crotalus adamanteus, Daboia siamensis, Macrovipera lebetina
Biochim. Biophys. Acta
395
455-467
1975
-
-
-
-
-
-
-
-
-
-
-
-
-
6
-
-
-
-
-
5
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
5
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
134118
Eckstein
Affinity chromatography of pho ...
Bothrops atrox, Crotalus adamanteus
Methods Enzymol.
34
605-610
1974
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
2
-
-
2
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
2
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
134120
Stulberg
The production of limit-oligon ...
Crotalus adamanteus
Methods Enzymol.
29E
477-482
1974
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
134121
Sulkowski
Venom exonuclease (phosphodies ...
Crotalus adamanteus
Biochem. Biophys. Res. Commun.
57
463-468
1974
-
-
-
-
-
1
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
134126
Dolapchiev
Purification of exonuclease (p ...
Crotalus adamanteus
Biochem. Biophys. Res. Commun.
61
273-281
1974
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
134122
Frischauf
Purification of a phosphodiest ...
Bothrops atrox
Eur. J. Biochem.
32
479-485
1973
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
1
-
-
1
1
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
1
1
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
134123
Sulkowski
-
Inactivation of 5'-nucleotidas ...
Crotalus adamanteus
Biochim. Biophys. Acta
240
443-447
1971
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
134124
Richards
Negative charge at the 3 termi ...
Crotalus adamanteus
Biochemistry
8
1786-1795
1969
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
2
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
2
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
134125
Hadjiolov
The action of snake venom phos ...
Crotalus adamanteus
Biochim. Biophys. Acta
142
111-127
1967
-
-
-
-
-
-
-
-
1
-
-
-
-
2
-
-
-
-
-
3
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
3
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
134127
Richards
Hydrolysis of dinucleoside mon ...
Crotalus adamanteus
Biochemistry
6
2908-2914
1967
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
1
-
2
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
2
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
134130
Laskowski
-
Exonuclease (phosphodiesterase ...
Bothrops atrox, Bungarus multicinctus, Crotalus adamanteus, Daboia siamensis, Deinagkistrodon acutus, Hemachatus haemachatus, Naja atra, Protobothrops mucrosquamatus, Trimeresurus gramineus
Procedures in Nucleic Acid Research (Cantoni, G. L. ; Davies, D. R. , eds. )
154-184
1966
-
-
-
-
-
-
9
-
-
-
-
-
-
9
-
-
2
-
-
9
-
-
18
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
9
-
-
-
-
-
-
-
-
-
2
-
9
-
-
18
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-