Crystallization (Comment) | Organism |
---|---|
in silico model for catalytic mechanism and development of a 3D pharmacophore model. Residues Arg99 and Gln109 are involved in the regulation of catalysis. The natural preference of the enzyme for poly(A) is based on favorable biophysical electrostatic and hydrophobic interactions | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
poly[2'-O-(2,4-dinitrophenyl)]poly-(A) | competitive | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | O95453 | - |
- |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.098 | - |
poly[2'-O-(2,4-dinitrophenyl)]poly-(A) | pH not specified in the publication, temperature not specified in the publication | Homo sapiens |