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Literature summary for 3.1.1.1 extracted from
- Imaging and detection of carboxylesterase in living cells and zebrafish pretreated with pesticides by a new near-infrared fluorescence off-on probe (2017), J. Agric. Food Chem., 65, 4209-4215 .
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Carbaryl | - |
Danio rerio |  |
| Carbaryl | 78% inhibition | Homo sapiens | |
| chlorpyrifos | - |
Danio rerio | |
| chlorpyrifos | 65% inhibition | Homo sapiens | |
| deltamethrin | - |
Danio rerio | |
| deltamethrin | 48% inhibition | Homo sapiens | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (E)-2-(2-(6-((4-acetoxybenzyl)oxy)-2,3-dihydro-1H-xanthen-4-yl)vinyl)-3,3-dimethyl-1-propyl-3H-indolium + H2O | Homo sapiens | - |
(E)-2-(2-(6-hydroxy-2,3-dihydro-1H-xanthen-4-yl)vinyl)-3,3-dimethyl-1-propyl-3H-indol-1-ium + 4-methylphenol + acetate | - |
? | |
| (E)-2-(2-(6-((4-acetoxybenzyl)oxy)-2,3-dihydro-1H-xanthen-4-yl)vinyl)-3,3-dimethyl-1-propyl-3H-indolium + H2O | Danio rerio | - |
(E)-2-(2-(6-hydroxy-2,3-dihydro-1H-xanthen-4-yl)vinyl)-3,3-dimethyl-1-propyl-3H-indol-1-ium + 4-methylphenol + acetate | - |
? | |
| additional information | Homo sapiens | imaging and detection of carboxylesterase in living cells by a near-infrared fluorescence off-on probe, overview | ? | - |
? | |
| additional information | Danio rerio | imaging and detection of carboxylesterase in zebrafish by a near-infrared fluorescence off-on probe, overview | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Danio rerio | - |
- |
- |
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| Hep-G2 cell | - |
Homo sapiens | - |
| yolk sac | - |
Danio rerio | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (E)-2-(2-(6-((4-acetoxybenzyl)oxy)-2,3-dihydro-1H-xanthen-4-yl)vinyl)-3,3-dimethyl-1-propyl-3H-indolium + H2O | - |
Homo sapiens | (E)-2-(2-(6-hydroxy-2,3-dihydro-1H-xanthen-4-yl)vinyl)-3,3-dimethyl-1-propyl-3H-indol-1-ium + 4-methylphenol + acetate | - |
? | |
| (E)-2-(2-(6-((4-acetoxybenzyl)oxy)-2,3-dihydro-1H-xanthen-4-yl)vinyl)-3,3-dimethyl-1-propyl-3H-indolium + H2O | - |
Danio rerio | (E)-2-(2-(6-hydroxy-2,3-dihydro-1H-xanthen-4-yl)vinyl)-3,3-dimethyl-1-propyl-3H-indol-1-ium + 4-methylphenol + acetate | - |
? | |
| additional information | imaging and detection of carboxylesterase in living cells by a near-infrared fluorescence off-on probe, overview | Homo sapiens | ? | - |
? | |
| additional information | imaging and detection of carboxylesterase in zebrafish by a near-infrared fluorescence off-on probe, overview | Danio rerio | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CES | - |
Homo sapiens |
| CES | - |
Danio rerio |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Homo sapiens |
| 37 | - |
assay at | Danio rerio |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.4 | - |
assay at | Homo sapiens |
| 7.4 | - |
assay at | Danio rerio |
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