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Literature summary for 2.9.1.2 extracted from
- Genetic analysis of selenocysteine biosynthesis in the archaeon Methanococcus maripaludis (2011), Mol. Microbiol., 81, 249-258.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Methanococcus maripaludis | Q6LZM9 | - |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| SelA | - |
Methanococcus maripaludis |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | Methanococcus maripaludis Mm900 is facultatively selenium-dependent with a single pathway of Sec-tRNASec formation. Seelenocysteine formation is abolished upon individually deleting the genes encoding selenophosphate synthetase, phosphoseryl-tRNASec kinase, or SepSecS. The resulting mutant strains can no longer grow on formate while growth with H2 + CO2 remains unaffected. Deletion of the phosphoseryl-tRNASec kinase and SepSecS genes is not possible unless the selenium-free [NiFe]-hydrogenases Frc and Vhc are expressed | Methanococcus maripaludis |
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