Cloned (Comment) | Organism |
---|---|
expressed in Sf9 insect cells | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | not inhibited by EDTA | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
additional information | divalent metal ions are not required for N-sulfotransferase activity of NDST-1 | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine | Homo sapiens | - |
adenosine 3',5'-bisphosphate + [heparan sulfate]-N-sulfoglucosamine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P52848 | - |
- |
Purification (Comment) | Organism |
---|---|
heparin-Toyopearl column chromatography and nickel-agarose column chromatography | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine | - |
Homo sapiens | adenosine 3',5'-bisphosphate + [heparan sulfate]-N-sulfoglucosamine | - |
? | |
additional information | NDST-1 is a bifunctional enzyme that displays N-deacetylase and N-sulfotransferase activities to convert an N-acetylated glucosamine residue to an N-sulfoglucosamine residue | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
N-deacetylase/N-sulfotransferase 1 | - |
Homo sapiens |
NDST-1 | - |
Homo sapiens |