Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.9.3 extracted from

  • da Silva, M.T.A.; Silva, I.R.E.; Faim, L.M.; Bellini, N.K.; Pereira, M.L.; Lima, A.L.; de Jesus, T.C.L.; Costa, F.C.; Watanabe, T.F.; Pereira, H.D.; Valentini, S.R.; Zanelli, C.F.; Borges, J.C.; Dias, M.V.B.; da Cunha, J.P.C.; Mittra, B.; Andrews, N.W.; Thiemann, O.H.
    Trypanosomatid selenophosphate synthetase structure, function and interaction with selenocysteine lyase (2020), PLoS Negl. Trop. Dis., 14, e0008091 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Trypanosoma cruzi
expression in Escherichia coli Leishmania major
expression in Eschetrichia coli Trypanosoma brucei brucei

Crystallization (Commentary)

Crystallization (Comment) Organism
-
Trypanosoma cruzi
-
Leishmania major
-
Trypanosoma brucei brucei

Organism

Organism UniProt Comment Textmining
Leishmania major Q4Q0M0
-
-
Trypanosoma brucei brucei Q38A34
-
-
Trypanosoma brucei brucei 927/4 GUTat10.1 Q38A34
-
-
Trypanosoma cruzi
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Trypanosoma cruzi
-
Leishmania major
-
Trypanosoma brucei brucei

Synonyms

Synonyms Comment Organism
selenophosphate synthetase
-
Trypanosoma cruzi
selenophosphate synthetase
-
Leishmania major
selenophosphate synthetase
-
Trypanosoma brucei brucei
SEPHS/SPS
-
Trypanosoma cruzi
SEPHS/SPS
-
Leishmania major
SEPHS/SPS
-
Trypanosoma brucei brucei

General Information

General Information Comment Organism
evolution the dimeric organization is functionally important throughout the domains of life Trypanosoma cruzi
evolution the dimeric organization is functionally important throughout the domains of life Leishmania major
evolution the dimeric organization is functionally important throughout the domains of life Trypanosoma brucei brucei
metabolism selenophosphate synthetase (SEPHS/SPS) plays an indispensable role in selenium metabolism, being responsible for catalyzing the formation of selenophosphate, the biological selenium donor for selenocysteine synthesis Trypanosoma cruzi
metabolism selenophosphate synthetase (SEPHS/SPS) plays an indispensable role in selenium metabolism, being responsible for catalyzing the formation of selenophosphate, the biological selenium donor for selenocysteine synthesis Leishmania major
metabolism selenophosphate synthetase (SEPHS/SPS) plays an indispensable role in selenium metabolism, being responsible for catalyzing the formation of selenophosphate, the biological selenium donor for selenocysteine synthesis Trypanosoma brucei brucei
physiological function the enzyme plays a role for the Trypanosoma brucei selenophosphate synthetase in the regulation of the ER stress response of the parasite Trypanosoma cruzi
physiological function the enzyme plays a role for the Trypanosoma brucei selenophosphate synthetase in the regulation of the parasite's ER stress response Leishmania major
physiological function the enzyme plays a role for the Trypanosoma brucei selenophosphate synthetase in the regulation of the parasite's ER stress response Trypanosoma brucei brucei