Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.9.3 extracted from

  • Oudouhou, F.; Casu, B.; Dopgwa Puemi, A.S.; Sygusch, J.; Baron, C.
    Analysis of Novel interactions between components of the selenocysteine biosynthesis pathway, SEPHS1, SEPHS2, SEPSECS, and SECp43 (2017), Biochemistry, 56, 2261-2270 .
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + selenide + H2O Homo sapiens
-
AMP + selenophosphate + phosphate
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q99611
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HEK-293T cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + selenide + H2O
-
Homo sapiens AMP + selenophosphate + phosphate
-
?

Subunits

Subunits Comment Organism
oligomer selenocysteine synthase (SEPSECS), SECp43, and selenophosphate synthetases SEPHS1 and SEPHS2 form oligomers in eukaryotic cells Homo sapiens

Synonyms

Synonyms Comment Organism
Sephs2
-
Homo sapiens

General Information

General Information Comment Organism
physiological function SEPHS2 is responsible for de novo synthesis of monoselenophosphate. SEPHS2 interacts with SEPSECS and SEPHS1 Homo sapiens