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Literature summary for 2.7.8.8 extracted from

  • Han, G.S.; Carman, G.M.
    Yeast PAH1-encoded phosphatidate phosphatase controls the expression of CHO1-encoded phosphatidylserine synthase for membrane phospholipid synthesis (2017), J. Biol. Chem., 292, 13230-13242 .
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae P08456
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-

Synonyms

Synonyms Comment Organism
CHO1
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Saccharomyces cerevisiae

Expression

Organism Comment Expression
Saccharomyces cerevisiae Cho1 expression in the Pah1 mutant lacking phosphatidate phosphatase is induced through the inositol-sensitive upstream activation sequence (UASINO), a cis-acting element for the phosphatidatecontrolled Henry (Ino2-Ino4/Opi1) regulatory circuit. Loss of the DGK1-encoded diacylglycerol kinase, which converts diacylglycerol to phosphatidate, partially suppresses the mutant Pah1-mediated induction of Cho1 and phosphatidylserine synthase activity additional information