BRENDA - Enzyme Database show
show all sequences of 2.7.8.42

A phosphoethanolamine transferase specific for the outer 3-deoxy-D-manno-octulosonic acid residue of Escherichia coli lipopolysaccharide. Identification of the eptB gene and Ca2+ hypersensitivity of an eptB deletion mutant

Reynolds, C.M.; Kalb, S.R.; Cotter, R.J.; Raetz, C.R.; J. Biol. Chem. 280, 21202-21211 (2005)

Data extracted from this reference:

Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
membrane
inner memebrane. Sequence predicts five trans-membrane segments within the N-terminal region
Escherichia coli
16020
-
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Escherichia coli
P37661
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-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
diacylphosphatidylethanolamine + alpha-D-Kdo-(2->4)-alpha-D-Kdo-(2->6)-lipid A
-
734149
Escherichia coli
diacylglycerol + 7-O-[2-aminoethoxy(hydroxy)phosphoryl]-alpha-D-Kdo-(2->4)-alpha-D-Kdo-(2->6)-lipid A
in the presence of Ca2+, enzyme transfers the phosphatidylethanolamine group. Stoichiometric amounts of diacylglycerol are generated during the transfer to Kdo2-lipid A
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-
?
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
membrane
inner memebrane. Sequence predicts five trans-membrane segments within the N-terminal region
Escherichia coli
16020
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
diacylphosphatidylethanolamine + alpha-D-Kdo-(2->4)-alpha-D-Kdo-(2->6)-lipid A
-
734149
Escherichia coli
diacylglycerol + 7-O-[2-aminoethoxy(hydroxy)phosphoryl]-alpha-D-Kdo-(2->4)-alpha-D-Kdo-(2->6)-lipid A
in the presence of Ca2+, enzyme transfers the phosphatidylethanolamine group. Stoichiometric amounts of diacylglycerol are generated during the transfer to Kdo2-lipid A
-
-
?
General Information
General Information
Commentary
Organism
physiological function
a gene replacement mutant is hypersensitive to CaCl2 at 5 mM or higher
Escherichia coli
General Information (protein specific)
General Information
Commentary
Organism
physiological function
a gene replacement mutant is hypersensitive to CaCl2 at 5 mM or higher
Escherichia coli
Other publictions for EC 2.7.8.42
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
739099
Moon
Complex transcriptional and po ...
Escherichia coli
Mol. Microbiol.
89
52-64
2013
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734192
Cullen
Characterization of unique mod ...
Campylobacter jejuni
J. Biol. Chem.
287
3326-3336
2012
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734149
Reynolds
A phosphoethanolamine transfer ...
Escherichia coli
J. Biol. Chem.
280
21202-21211
2005
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734135
Kanipes
Ca2+-induced phosphoethanolami ...
Escherichia coli
J. Biol. Chem.
276
1156-1163
2001
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