Literature summary for 2.7.8.41 extracted from

Kusaka, J.; Shuto, S.; Imai, Y.; Ishikawa, K.; Saito, T.; Natori, K.; Matsuoka, S.; Hara, H.; Matsumoto, K.
Septal localization by membrane targeting sequences and a conserved sequence essential for activity at the COOH-terminus of Bacillus subtilis cardiolipin synthase (2016), Res. Microbiol., 167, 202-214 .

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Protein Variants

Protein Variants	Comment	Organism
L482Delta	deletion of the last residue, abolishes cardiolipin synthesis	Bacillus subtilis
additional information	ClsA derivatives with deletions starting from the COOH-terminus (Leu482) no longer localize to the septum if the deletion passes the Ile residue at position 448. Amphipathic helices formed by Ile436-Leu450 and Leu466-Leu478, are responsible for septal localization. Deletion of the C-terminal 34, 7 or 10 residues abolishes cardiolipin synthesis	Bacillus subtilis

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
membrane	septal membrane	Bacillus subtilis	16020	-

Organism

Organism	UniProt	Comment	Textmining
Bacillus subtilis	P71040	major cardiolipin synthase ClsA	-
Bacillus subtilis 168	P71040	major cardiolipin synthase ClsA	-

Synonyms

Synonyms	Comment	Organism
clsA	-	Bacillus subtilis

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Release 2023.1 (January 2023)