Literature summary for 2.7.7.7 extracted from

Raper, A.T.; Suo, Z.
Investigation of intradomain motions of a Y-family DNA polymerase during substrate binding and catalysis (2016), Biochemistry, 55, 5832-5844 .

Search for more literature for 2.7.7.7

Organism

Organism	UniProt	Comment	Textmining
Saccharolobus solfataricus	Q97W02	-	-
Saccharolobus solfataricus ATCC 35092	Q97W02	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
a 2'-deoxyribonucleoside 5'-triphosphate + DNAn	the complex DNA binding mechanism of a Y-family DNA polymerase involves aspects of both induced-fit and conformational selection mechanisms. Intradomain protein motions are observed throughout nucleotide binding and incorporation, some of which may kinetically limit the rate of correct nucleotide incorporation	Saccharolobus solfataricus	diphosphate + DNAn+1	-	?
a 2'-deoxyribonucleoside 5'-triphosphate + DNAn	the complex DNA binding mechanism of a Y-family DNA polymerase involves aspects of both induced-fit and conformational selection mechanisms. Intradomain protein motions are observed throughout nucleotide binding and incorporation, some of which may kinetically limit the rate of correct nucleotide incorporation	Saccharolobus solfataricus ATCC 35092	diphosphate + DNAn+1	-	?

Synonyms

Synonyms	Comment	Organism
Dpo4	-	Saccharolobus solfataricus

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Release 2023.1 (January 2023)