Inhibitors | Comment | Organism | Structure |
---|---|---|---|
d(Ap4C) | d(Ap4T), d(Ap4C) and d(Ap4G) inhibit the incorporation of dATP into DNA less effectively than d(Ap4T), d(Tp4T) and d(Tp4C) the dTTP incorporation | Escherichia coli | |
d(Ap4G) | d(Ap4T), d(Ap4C) and d(Ap4G) inhibit the incorporation of dATP into DNA less effectively than d(Ap4T), d(Tp4T) and d(Tp4C) the dTTP incorporation | Escherichia coli | |
d(Ap4T) | d(Ap4T), d(Ap4C) and d(Ap4G) inhibit the incorporation of dATP into DNA less effectively than d(Ap4T), d(Tp4T) and d(Tp4C) the dTTP incorporation | Escherichia coli | |
d(Tp4C) | d(Ap4T), d(Ap4C) and d(Ap4G) inhibit the incorporation of dATP into DNA less effectively than d(Ap4T), d(Tp4T) and d(Tp4C) the dTTP incorporation | Escherichia coli | |
d(Tp4T) | d(Ap4T), d(Ap4C) and d(Ap4G) inhibit the incorporation of dATP into DNA less effectively than d(Ap4T), d(Tp4T) and d(Tp4C) the dTTP incorporation | Escherichia coli |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0004 | - |
dTTP | - |
Escherichia coli | |
0.00072 | - |
d(Tp4T) | - |
Escherichia coli | |
0.00174 | - |
d(Tp4G) | - |
Escherichia coli | |
0.00211 | - |
d(Ap4T) | - |
Escherichia coli | |
0.00222 | - |
d(Tp4C) | - |
Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
d(Ap4T) + RNAn | primer elongation | Escherichia coli | ? | - |
? | |
d(TP4C) + RNAn | primer elongation | Escherichia coli | ? | - |
? | |
d(Tp4G) + RNAn | primer elongation | Escherichia coli | ? | - |
? | |
d(Tp4T) + RNAn | primer elongation | Escherichia coli | ? | - |
? | |
dTTP + RNAn | primer elongation | Escherichia coli | ? | - |
? | |
additional information | dinucleoside teraphosphates are more potent substrates than dinucleoside triphosphates and dinucleoside pentaphosphates | Escherichia coli | ? | - |
? |