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Literature summary for 2.7.7.3 extracted from

  • Gupta, A.; Singh, P.K.; Iqbal, N.; Sharma, P.; Baraigya, H.R.; Kaur, P.; Umar, M.S.; Ahmad, F.; Sharma, A.; Owais, M.; Sharma, S.; Singh, T.P.
    Structural and binding studies of phosphopantetheine adenylyl transferase from Acinetobacter baumannii (2019), Biochim. Biophys. Acta, 1867, 537-547 .
    View publication on PubMed
Search for more literature for 2.7.7.3

Cloned(Commentary)

Cloned (Comment) Organism
-
 Acinetobacter baumannii

Crystallization (Commentary)

Crystallization (Comment) Organism
in complex with sodium citrate, to 1.76 A resolution. Citrate binds at the ATP binding site Acinetobacter baumannii

Inhibitors

Inhibitors Comment Organism Structure
L-ascorbate
-
 Acinetobacter baumannii
Sodium citrate
-
 Acinetobacter baumannii

Organism

Organism UniProt Comment Textmining
Acinetobacter baumannii B0VTH7
-
-
Acinetobacter baumannii SDF B0VTH7
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
diphosphate + 3'-dephospho-CoA
-
 Acinetobacter baumannii ATP + pantetheine 4'-phosphate
-
 r
diphosphate + 3'-dephospho-CoA
-
 Acinetobacter baumannii SDF ATP + pantetheine 4'-phosphate
-
 r

Synonyms

Synonyms Comment Organism
CoaD
-
 Acinetobacter baumannii
PPAT
-
 Acinetobacter baumannii

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.000018
-
 pH not specified in the publication, temperature not specified in the publication Acinetobacter baumannii Sodium citrate
0.027
-
 pH not specified in the publication, temperature not specified in the publication Acinetobacter baumannii L-ascorbate