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Literature summary for 2.7.7.18 extracted from

  • Han, S.; Forman, M.D.; Loulakis, P.; Rosner, M.H.; Xie, Z.; Wang, H.; Danley, D.E.; Yuan, W.; Schafer, J.; Xu, Z.
    Crystal structure of nicotinic acid mononucleotide adenylyltransferase from Staphyloccocus aureus: structural basis for NaAD interaction in functional dimer (2006), J. Mol. Biol., 360, 814-825.
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
Crystals of saNaMNAT were initially obtained at 22Ā°C from polyethylene glycol 3000 and phosphatecitrate buffer. Staphylococcus aureus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
44000
-
by gel filtration Staphylococcus aureus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
nicotinic acid mononucleotide + ATP Methanothermobacter thermautotrophicus
-
nicotinic acid dinucleotide + diphosphate
-
?
nicotinic acid mononucleotide + ATP Bacillus subtilis
-
nicotinic acid dinucleotide + diphosphate
-
?
nicotinic acid mononucleotide + ATP Staphylococcus aureus
-
nicotinic acid dinucleotide + diphosphate
-
?
nicotinic acid mononucleotide + ATP Staphylococcus aureus COL
-
nicotinic acid dinucleotide + diphosphate
-
?

Organism

Organism UniProt Comment Textmining
Bacillus subtilis P54455
-
-
Methanothermobacter thermautotrophicus
-
-
-
Staphylococcus aureus Q5HFG7
-
-
Staphylococcus aureus COL Q5HFG7
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
nicotinic acid mononucleotide + ATP
-
Methanothermobacter thermautotrophicus nicotinic acid dinucleotide + diphosphate
-
?
nicotinic acid mononucleotide + ATP
-
Bacillus subtilis nicotinic acid dinucleotide + diphosphate
-
?
nicotinic acid mononucleotide + ATP
-
Staphylococcus aureus nicotinic acid dinucleotide + diphosphate
-
?
nicotinic acid mononucleotide + ATP
-
Staphylococcus aureus COL nicotinic acid dinucleotide + diphosphate
-
?

Subunits

Subunits Comment Organism
dimer
-
Bacillus subtilis
hexamer
-
Methanothermobacter thermautotrophicus

Synonyms

Synonyms Comment Organism
NaMNAT
-
Methanothermobacter thermautotrophicus
NaMNAT
-
Bacillus subtilis
NaMNAT
-
Staphylococcus aureus
nicotinic acid mononucleotide adenylyltransferase
-
Methanothermobacter thermautotrophicus
nicotinic acid mononucleotide adenylyltransferase
-
Bacillus subtilis
nicotinic acid mononucleotide adenylyltransferase
-
Staphylococcus aureus