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Literature summary for 2.7.7.101 extracted from
- In the Bacillus stearothermophilus DnaB-DnaG complex, the activities of the two proteins are modulated by distinct but overlapping networks of residues (2006), J. Bacteriol., 188, 1534-1539 .
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Geobacillus stearothermophilus | Q9X4D0 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | enzyme initiates at 3'-ATC-5' and 3'-ATT-5' sites synthesizing primers that are 22 or 23 nucleotides long | Geobacillus stearothermophilus | ? | - |
? |  |
| ssDNA + n NTP | - |
Geobacillus stearothermophilus | ssDNA/pppN(pN)n-1 hybrid + (n-1) diphosphate | - |
? | |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | in the presence of the helicase DnaB the size distribution of primers is different, and a range of additional smaller primers are also synthesized. Mutations E15A, Y88A, and E15A Y88A in DnaB bind DnaG but are not able to modulate primer size, whereas the R195A/M196A mutant inhibits the primase activity | Geobacillus stearothermophilus |
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