Activating Compound | Comment | Organism | Structure |
---|---|---|---|
2-oxoglutarate | activation | Rattus norvegicus | |
alanine | activation | Rattus norvegicus | |
CDP | activation | Rattus norvegicus | |
cis-aconitate | activation | Rattus norvegicus | |
citrate | activation | Rattus norvegicus | |
dithiothreitol | not | Rattus norvegicus | |
fumarate | activation | Rattus norvegicus | |
GDP | activation | Rattus norvegicus | |
isocitrate | activation | Rattus norvegicus | |
L-histidine | activation | Rattus norvegicus | |
malate | activation | Rattus norvegicus | |
additional information | no activation by GTP, CTP, UTP, TTP, 2'-dGTP, 2'-dCTP, 2'-dATP, GMP, CMP, UMP, TMP, IMP, 2'-dAMP or 3',5'-cAMP | Rattus norvegicus | |
additional information | no activation by succinate or oxaloacetate | Rattus norvegicus | |
Prostaglandins | activation | Rattus norvegicus | |
TDP | activation | Rattus norvegicus | |
threonine | activation | Rattus norvegicus | |
UDP | activation | Rattus norvegicus |
General Stability | Organism |
---|---|
repeated freeze-thawing inactivates | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
oleic acid | - |
Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
1.9 | - |
AMP | 37°C, pH 7.0 | Rattus norvegicus | |
7 | - |
ATP | 37°C, pH 7.0 | Rattus norvegicus | |
16.8 | - |
ADP | 37°C, pH 7.0 | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Rattus norvegicus | 5739 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | - |
Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
11000 | - |
2 * 13000 + 1 * 11000, SDS-PAGE | Rattus norvegicus |
13000 | - |
2 * 13000 + 1 * 11000, SDS-PAGE | Rattus norvegicus |
46000 | 49000 | analytical ultracentrifugation | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
1000 | - |
- |
Rattus norvegicus |
Storage Stability | Organism |
---|---|
4°C, 5 mM sodium phosphate, pH 7, 1 mM 2-mercaptoethanol, 1 month | Rattus norvegicus |
frozen, up to 6 months | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ADP + ADP | - |
Rattus norvegicus | ATP + AMP | - |
r | |
ATP + AMP | no substrates are ATP/dGMP | Rattus norvegicus | ADP + ADP | - |
r | |
ATP + AMP | no substrates are 3',5'-cAMP, dAMP, 2'-AMP, 3'-AMP | Rattus norvegicus | ADP + ADP | - |
r | |
ATP + AMP | no substrates are ATP/IMP | Rattus norvegicus | ADP + ADP | - |
r | |
ATP + AMP | no substrates are ATP/UMP | Rattus norvegicus | ADP + ADP | - |
r | |
ATP + AMP | no substrates are ATP/TMP | Rattus norvegicus | ADP + ADP | - |
r | |
ATP + AMP | no substrates are ATP/GMP | Rattus norvegicus | ADP + ADP | - |
r | |
dATP + AMP | - |
Rattus norvegicus | dADP + ADP | - |
? | |
dGTP + AMP | - |
Rattus norvegicus | dGDP + ADP | - |
? |
Subunits | Comment | Organism |
---|---|---|
trimer | 2 * 13000 + 1 * 11000, SDS-PAGE | Rattus norvegicus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Rattus norvegicus |