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Literature summary for 2.7.4.21 extracted from

  • Nagpal, L.; Fu, C.; Snyder, S.H.
    Inositol hexakisphosphate kinase-2 in cerebellar granule cells regulates Purkinje cells and motor coordination via protein 4.1N (2018), J. Neurosci., 38, 7409-7419 .
    View publication on PubMedView publication on EuropePMC
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Organism

Organism UniProt Comment Textmining
Mus musculus Q80V72
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-

Source Tissue

Source Tissue Comment Organism Textmining
cerebellar granule cell
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 Mus musculus
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Synonyms

Synonyms Comment Organism
inositol hexakisphosphate kinase-2
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 Mus musculus
IP6K2
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 Mus musculus

General Information

General Information Comment Organism
malfunction deletion of IP6K2 in male/female mice elicits substantial defects in synaptic influences of granule cells upon Purkinje cells as well as notable impairment of locomotor function. The disruption of IP6K2- 4.1N interactions impairs cell viability Mus musculus
physiological function inositol hexakisphosphate kinase-2 in cerebellar granule cells regulates Purkinje cells and motor coordination via protein 4.1N Mus musculus