Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.3.3 extracted from

  • Fuhrmann, J.; Schmidt, A.; Spiess, S.; Lehner, A.; Turgay, K.; Mechtler, K.; Charpentier, E.; Clausen, T.
    McsB is a protein arginine kinase that phosphorylates and inhibits the heat-shock regulator CtsR (2009), Science, 324, 1323-1327.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Bacillus subtilis
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + CtsR-L-Arg McsB specifically phosphorylates arginine residues in the DNA binding domain of CtsR, thereby impairing its function as a repressor of stress response genes, phosphorylation of CtsR by McsB is sufficient to inhibit the repressor function of CtsR Bacillus subtilis ADP + CtsR-N-phospho-L-Arg
-
?
ATP + L-Arg McsB acts exclusively on L-Arg residues Bacillus subtilis ADP + Nomega-phospho-L-Arg
-
?

Synonyms

Synonyms Comment Organism
McsB
-
Bacillus subtilis

Cofactor

Cofactor Comment Organism Structure
ATP
-
Bacillus subtilis