Inhibitors | Comment | Organism | Structure |
---|---|---|---|
PMCA4b | wild-type PMCA4b inhibits CASK activity, while PMCA4b mutant D672E, containing a point mutation in the ATP binding site, shows only 10% of the wild-type inhibitory potency | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
plasma membrane | - |
Rattus norvegicus | 5886 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Rattus norvegicus | CASK in inhibited by the plasma membrane Ca2+ pump 4b/CI, PMCA4b, via direct interaction with the C-terminus of the Ca2+ transporter | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Rattus norvegicus | - |
kidney | - |
Rattus norvegicus | - |
liver | high activity | Rattus norvegicus | - |
lung | low activity | Rattus norvegicus | - |
spleen | very low activity | Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | CASK in inhibited by the plasma membrane Ca2+ pump 4b/CI, PMCA4b, via direct interaction with the C-terminus of the Ca2+ transporter | Rattus norvegicus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Ca2+/calmodulin-dependent membrane-associated kinase | - |
Rattus norvegicus |
CASK | - |
Rattus norvegicus |
More | the enzyme is a member of the MAGUK family | Rattus norvegicus |