Application | Comment | Organism |
---|---|---|
medicine | IKKbeta-targeted NF-kappaB blockade is an attractive therapeutic approach for the prevention of colitis-associated tumors | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
IMD-0354 | - |
Mus musculus | |
NBD peptide | NEMO-binding domain peptide | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + [IkappaB protein] | Mus musculus | - |
ADP + [IkappaB phosphoprotein] | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
colon | - |
Mus musculus | - |
J-774.1 cell | - |
Mus musculus | - |
macrophage | - |
Mus musculus | - |
MC-38 cell | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + [IkappaB protein] | - |
Mus musculus | ADP + [IkappaB phosphoprotein] | - |
? |
Subunits | Comment | Organism |
---|---|---|
heterotrimer | IkappaB kinase, IKK, consists of two catalytic subunits, IKKalpha and IKKbeta, and a regulatory subunit IKKgamma, NEMO | Mus musculus |
Synonyms | Comment | Organism |
---|---|---|
IkappaB kinase beta | - |
Mus musculus |
IKKbeta | - |
Mus musculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Mus musculus |