Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | - |
Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 2'-deoxycytidine | Homo sapiens | - |
ADP + 2'-deoxycytidine 5'-phosphate | - |
? | |
ATP + cytarabine | Homo sapiens | drug against acute myeloid and lymphoblastic leukemia | ADP + cytarabine 5'-phosphate | - |
? | |
additional information | Homo sapiens | resistance of cells to cytarabine is caused by dCK enzyme deficiency | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain tumor cell | low enzyme expression level | Homo sapiens | - |
additional information | high enzyme expression level in case of acute myeloid leukemia and acute lymphoblastic leukemia, sensitivity of cell types to cytarabine, overview | Homo sapiens | - |
retinoblastoma cell | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
MTT assay method | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 2'-deoxycytidine | - |
Homo sapiens | ADP + 2'-deoxycytidine 5'-phosphate | - |
? | |
ATP + cytarabine | drug against acute myeloid and lymphoblastic leukemia | Homo sapiens | ADP + cytarabine 5'-phosphate | - |
? | |
ATP + cytarabine | i.e. 1-beta-D-arabinofuranosylcytosine | Homo sapiens | ADP + cytarabine 5'-phosphate | - |
? | |
additional information | resistance of cells to cytarabine is caused by dCK enzyme deficiency | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
dCK | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Homo sapiens |