Literature summary for 2.7.1.217 extracted from

Zhang, X.; Carter, M.; Vetting, M.; Francisco, B.; Zhao, S.; Al-Obaidi, N.; Solbiati, J.; Thiaville, J.; Crecy-Lagard, V.; Jacobson, M.; Almo, S.; Gerlt, J.
Assignment of function to a domain of unknown function: DUF1537 is a new kinase family in catabolic pathways for acid sugars (2016), Proc. Natl. Acad. Sci. USA, 113, E4161-E4169.

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Organism

Organism	UniProt	Comment	Textmining
Cupriavidus necator	Q0KBC8	-	-
Cupriavidus necator DSM 428	Q0KBC8	-	-
Salmonella enterica subsp. enterica serovar Typhimurium	Q8ZMG5	-	-
Salmonella enterica subsp. enterica serovar Typhimurium ATCC 700720	Q8ZMG5	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + 3-dehydro-D-erythronate	-	Cupriavidus necator	ADP + 3-dehydro-4-phospho-D-erythronate	-	?
ATP + 3-dehydro-D-erythronate	-	Salmonella enterica subsp. enterica serovar Typhimurium	ADP + 3-dehydro-4-phospho-D-erythronate	-	?
ATP + 3-dehydro-D-erythronate	-	Salmonella enterica subsp. enterica serovar Typhimurium ATCC 700720	ADP + 3-dehydro-4-phospho-D-erythronate	-	?
ATP + 3-dehydro-D-erythronate	-	Cupriavidus necator DSM 428	ADP + 3-dehydro-4-phospho-D-erythronate	-	?
ATP + 3-dehydro-L-erythronate	-	Cupriavidus necator	ADP + 3-dehydro-4-phospho-L-erythronate	-	?
ATP + 3-dehydro-L-erythronate	-	Salmonella enterica subsp. enterica serovar Typhimurium	ADP + 3-dehydro-4-phospho-L-erythronate	-	?
ATP + 3-dehydro-L-erythronate	-	Salmonella enterica subsp. enterica serovar Typhimurium ATCC 700720	ADP + 3-dehydro-4-phospho-L-erythronate	-	?
ATP + 3-dehydro-L-erythronate	-	Cupriavidus necator DSM 428	ADP + 3-dehydro-4-phospho-L-erythronate	-	?

Synonyms

Synonyms	Comment	Organism
3-oxo-tetronate kinase	-	Cupriavidus necator
3-oxo-tetronate kinase	-	Salmonella enterica subsp. enterica serovar Typhimurium
otnK	-	Cupriavidus necator
otnK	-	Salmonella enterica subsp. enterica serovar Typhimurium

General Information

General Information	Comment	Organism
physiological function	involved in utilization of L-threonate and D-erythronate, with different dehydrogenases generating the 2-oxo-tetronate that is isomerized to 3-oxo-tetronate by OtnI, phosphorylated to 3-oxo-tetronate 4-phosphate by OtnK, and decarboxylated to DHAP and CO2	Cupriavidus necator
physiological function	involved in utilization of L-threonate and D-erythronate, with different dehydrogenases generating the 2-oxo-tetronate that is isomerized to 3-oxo-tetronate by OtnI, phosphorylated to 3-oxo-tetronate 4-phosphate by OtnK, and decarboxylated to DHAP and CO2	Salmonella enterica subsp. enterica serovar Typhimurium

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Release 2023.1 (January 2023)