BRENDA - Enzyme Database show
show all sequences of 2.7.1.201

The trehalose phosphotransferase system (PTS) in E. coli W can transport low levels of sucrose that are sufficient to facilitate induction of the csc sucrose catabolism operon

Steen, J.A.; Bohlke, N.; Vickers, C.E.; Nielsen, L.K.; PLoS ONE 9, e88688 (2014)

Data extracted from this reference:

Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
membrane
-
Escherichia coli
16020
-
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
[protein]-Npi-phospho-L-histidine + alpha,alpha-trehalose[side 1]
Escherichia coli
-
[protein]-L-histidine + alpha,alpha-trehalose 6-phosphate[side 2]
-
-
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Escherichia coli
A0A0H3F7X9
-
-
Escherichia coli
-
-
-
Escherichia coli DSM 1116
A0A0H3F7X9
-
-
Posttranslational Modification
Posttranslational Modification
Commentary
Organism
phosphoprotein
-
Escherichia coli
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
additional information
the enzyme is also capable of sucrose transport
737143
Escherichia coli
?
-
-
-
-
[protein]-Npi-phospho-L-histidine + alpha,alpha-trehalose[side 1]
-
737143
Escherichia coli
[protein]-L-histidine + alpha,alpha-trehalose 6-phosphate[side 2]
-
-
-
?
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
membrane
-
Escherichia coli
16020
-
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
[protein]-Npi-phospho-L-histidine + alpha,alpha-trehalose[side 1]
Escherichia coli
-
[protein]-L-histidine + alpha,alpha-trehalose 6-phosphate[side 2]
-
-
?
Posttranslational Modification (protein specific)
Posttranslational Modification
Commentary
Organism
phosphoprotein
-
Escherichia coli
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
additional information
the enzyme is also capable of sucrose transport
737143
Escherichia coli
?
-
-
-
-
[protein]-Npi-phospho-L-histidine + alpha,alpha-trehalose[side 1]
-
737143
Escherichia coli
[protein]-L-histidine + alpha,alpha-trehalose 6-phosphate[side 2]
-
-
-
?
General Information
General Information
Commentary
Organism
physiological function
deletion of repressor TreR enables uptake of sucrose via TreB. Once inside the cell, this sucrose is not processed by the TreC hydrolase, nor is it sufficient for growth of the strain. Levels of cscA (invertase) transcript increase in the treR mutant relative to the wild-type strain when grown under low sucrose conditions; the trehalose-specific enzyme II is required for growth of Escherichia coli strain WDELTAtreR on low sucrose
Escherichia coli
General Information (protein specific)
General Information
Commentary
Organism
physiological function
the trehalose-specific enzyme II is required for growth of Escherichia coli strain WDELTAtreR on low sucrose
Escherichia coli
physiological function
deletion of repressor TreR enables uptake of sucrose via TreB. Once inside the cell, this sucrose is not processed by the TreC hydrolase, nor is it sufficient for growth of the strain. Levels of cscA (invertase) transcript increase in the treR mutant relative to the wild-type strain when grown under low sucrose conditions
Escherichia coli
Other publictions for EC 2.7.1.201
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [C]
Temperature Range [C]
Temperature Stability [C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [C] (protein specific)
Temperature Range [C] (protein specific)
Temperature Stability [C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
737143
Steen
The trehalose phosphotransfera ...
Escherichia coli, Escherichia coli DSM 1116
PLoS ONE
9
e88688
2014
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736763
Andre
Glucose and trehalose PTS perm ...
Spiroplasma citri
Microbiology
149
2687-2696
2003
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736338
Klein
Molecular analysis of treB enc ...
Escherichia coli
J. Bacteriol.
177
4043-4052
1995
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736332
Boos
Trehalose transport and metabo ...
Escherichia coli
J. Bacteriol.
172
3450-3461
1990
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736331
Postma
Transport of trehalose in Salm ...
no activity in Salmonella typhimurium
J. Bacteriol.
168
1107-1111
1986
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