Activating Compound | Comment | Organism | Structure |
---|---|---|---|
ADP | activates | Methanococcus maripaludis | |
AMP | activates | Methanococcus maripaludis | |
citrate | activates the enzyme in the absence of phosphate and inhibits the enzyme in the presence of phosphate | Methanococcus maripaludis | |
GDP | activates the enzyme in the absence of phosphate and inhibits the enzyme in the presence of phosphate | Methanococcus maripaludis | |
phosphate | activates | Methanococcus maripaludis |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(NH4)2SO4 | inhibits above 50 mM | Methanococcus maripaludis | |
citrate | activates the enzyme in the absence of phosphate and inhibits the enzyme in the presence of phosphate | Methanococcus maripaludis | |
GDP | activates the enzyme in the absence of phosphate and inhibits the enzyme in the presence of phosphate | Methanococcus maripaludis | |
KCl | inhibits above 50 mM | Methanococcus maripaludis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Methanococcus maripaludis | - |
- |
- |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.0056 | - |
pH 6.0, 37°C, activity in undialyzed cell extracts | Methanococcus maripaludis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + D-fructose 6-phosphate | - |
Methanococcus maripaludis | ADP + D-fructose 1,6-bisphosphate | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Methanococcus maripaludis |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6 | - |
- |
Methanococcus maripaludis |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
5.5 | 6.5 | about 50% of maximal activity at pH 5.5, about 25% of maximal activity at pH 6.5 | Methanococcus maripaludis |
Organism | Comment | Expression |
---|---|---|
Methanococcus maripaludis | in the culture, H2 plus CO2 gas is replaced with N2 plus CO2 gas after 1.7 days in an attempt to induce glycogen mobilization. This attempt was unsuccessful, because the glycogen content is unchanged. The specific activity of 6-phosphofructokinase increases 2- to 2.5-fold. This result suggests that changes in the levels of 6-phosphofructokinase alone are insufficient to affect glycogen mobilization | up |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme is involved in glycogen catabolism | Methanococcus maripaludis |