Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | D-glucose 1,6-bisphosphate and phosphoenolpyruvate have no effect on activity | Teladorsagia circumcincta |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ATP | allosteric inhibition by high ATP concentrations. The inhibitory effects of high ATP concentration can be reversed by D-fructose 2,6-bisphosphate and AMP | Teladorsagia circumcincta | |
citrate | mild inhibitory effects, but only at concentrations exceeding 2 mM | Teladorsagia circumcincta | |
isocitrate | mild inhibitory effects, but only at concentrations exceeding 2 mM | Teladorsagia circumcincta | |
malate | mild inhibitory effects, but only at concentrations exceeding 2 mM | Teladorsagia circumcincta |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Teladorsagia circumcincta | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adult | - |
Teladorsagia circumcincta | - |
larva | - |
Teladorsagia circumcincta | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + D-fructose 6-phosphate | - |
Teladorsagia circumcincta | ADP + D-fructose 1,6-bisphosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
hosphofructokinase-1 | - |
Teladorsagia circumcincta |
PFK-1 | - |
Teladorsagia circumcincta |
Organism | Comment | Expression |
---|---|---|
Teladorsagia circumcincta | enzyme activities are higher in the adult stage as compared to L3 larval stages | up |