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Literature summary for 2.6.1.64 extracted from
- Purification, characterization and identification of rat brain cytosolic tyrosine transaminase as glutamine transaminase-K (2020), Neurochem. Int., 133, 104653 .
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Rattus norvegicus | 5829 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-glutamine + phenylpyruvate | Rattus norvegicus | - |
2-oxoglutaramate + L-phenylalanine | - |
? |  |
| L-glutamine + phenylpyruvate | Rattus norvegicus Wistar | - |
2-oxoglutaramate + L-phenylalanine | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
| Rattus norvegicus Wistar | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| native enzyme from rat brain by ultracentrifugation at 220000 x g, followed by ammonium sulfate fractionation, hydropbobic interaction chromatography, anion exchange chromatography, and hydroxyapatite chromatography | Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Rattus norvegicus | - |
| cerebellum | - |
Rattus norvegicus | - |
| cerebral cortex | - |
Rattus norvegicus | - |
| corpus striatum | - |
Rattus norvegicus | - |
| hypothalamus | - |
Rattus norvegicus | - |
| medulla oblongata | - |
Rattus norvegicus | - |
| midbrain | - |
Rattus norvegicus | - |
| pons | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-glutamine + phenylpyruvate | - |
Rattus norvegicus | 2-oxoglutaramate + L-phenylalanine | - |
? | |
| L-glutamine + phenylpyruvate | - |
Rattus norvegicus Wistar | 2-oxoglutaramate + L-phenylalanine | - |
? | |
| additional information | analysis of the enzyme's substrate and 2-oxoacid cosubstrate specificities. Differentiation of the enzyme activity from tyrosine transaminase, EC 2.6.1.5, detailed overview | Rattus norvegicus | ? | - |
- |
|
| additional information | analysis of the enzyme's substrate and 2-oxoacid cosubstrate specificities. Differentiation of the enzyme activity from tyrosine transaminase, EC 2.6.1.5, detailed overview | Rattus norvegicus Wistar | ? | - |
- |
|
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Gln/phenylpyruvate transaminase | - |
Rattus norvegicus |
| glutamine transaminase-K | - |
Rattus norvegicus |
| glutamine/phenylpyruvate transaminase | - |
Rattus norvegicus |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Rattus norvegicus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8.5 | - |
assay at | Rattus norvegicus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| pyridoxal 5'-phosphate | - |
Rattus norvegicus | |
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Release 2023.1 (January 2023)
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