Protein Variants | Comment | Organism |
---|---|---|
C321M | no enzymic activity, behaves as monomer even in absence of 2-mercaptoethanol | Homo sapiens |
C321S | no enzymic activity, behaves as monomer even in absence of 2-mercaptoethanol | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
5,5'-dithiobis-2-nitrobenzoic acid | 95% loss of activity | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
50000 | - |
2 * 50000, SDS-PAGE, presence of 2-mercaptoethanol | Homo sapiens |
100000 | - |
SDS-PAGE, absence of 2-mercaptoethanol | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
17.5 | - |
pH 8.4, 25°C | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-aminobutanoate + 2-oxoglutarate | - |
Homo sapiens | 4-oxobutanoate + L-glutamate | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | 2 * 50000, SDS-PAGE, presence of 2-mercaptoethanol | Homo sapiens |