Application | Comment | Organism |
---|---|---|
medicine | generation of a chimeric protein (BLS-FliC131) by fusing flagellin from Salmonella typhimurium in the N-termini of BLS. The fusion protein is recognized by anti-flagellin and anti-BLS antibodies, keeps the oligomerization capacity of BLS, without affecting the folding of the monomeric protein components. The thermal stability of each fusion partner is conserved. BLS-FliC131 retains the capacity of triggering TLR5. The humoral response against BLS elicited by BLS-FliC131 is stronger than the one elicited by equimolar amounts of BLS1FliC | Brucella abortus |
Protein Variants | Comment | Organism |
---|---|---|
additional information | generation of a chimeric protein (BLS-FliC131) by fusing flagellin from Salmonella typhimurium in the N-termini of BLS. The fusion protein is recognized by anti-flagellin and anti-BLS antibodies, keeps the oligomerization capacity of BLS, without affecting the folding of the monomeric protein components. The thermal stability of each fusion partner is conserved. BLS-FliC131 retains the capacity of triggering TLR5. The humoral response against BLS elicited by BLS-FliC131 is stronger than the one elicited by equimolar amounts of BLS1FliC | Brucella abortus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Brucella abortus | Q2YKV1 | - |
- |
Brucella abortus 2308 | Q2YKV1 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
BLS | - |
Brucella abortus |
RibH2 | - |
Brucella abortus |