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Literature summary for 2.5.1.63 extracted from
- A coupled chlorinase-fluorinase system with a high efficiency of trans-halogenation and a shared substrate tolerance (2018), Chem. Commun. (Camb.), 54, 9458-9461 .
Application
| Application | Comment | Organism |
|---|---|---|
| synthesis | deveopment of a coupled chlorinase-fluorinase system for rapid transhalogenation. The chlorinase shares a substrate tolerance with the fluorinase, enabling these two enzymes to cooperatively produce 5'-fluorodeoxy-2-ethynyladenosine (5'-FDEA) in up to 91.6% yield in 1 h | Streptomyces sp. MA37 |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Streptomyces sp. MA37 | W0W999 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 2'-deoxy-2-ethynyladenosyl-L-methionine + fluoride | - |
Streptomyces sp. MA37 | 2'-deoxy-2-ethynyl-5'-fluoroadenosine + L-methionine | - |
r |  |
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