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Literature summary for 2.5.1.63 extracted from

  • Yeo, W.; Chew, X.; Smith, D.; Chan, K.; Sun, H.; Zhao, H.; Lim, Y.; Ang, E.
    Probing the molecular determinants of fluorinase specificity (2017), Chem. Commun. (Camb.), 53, 2559-2562 .
    View publication on PubMed
Search for more literature for 2.5.1.63

Protein Variants

Protein Variants Comment Organism
A279L mutant with increased activity towards unnatural substrates Streptomyces sp. MA37
F213Y mutant with increased activity towards unnatural substrates Streptomyces sp. MA37
F213Y/ A279L mutant with increased activity towards unnatural substrates Streptomyces sp. MA37

Organism

Organism UniProt Comment Textmining
Streptomyces sp. MA37 W0W999
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2'-deoxyadenosyl-L-methionine + fluoride
-
 Streptomyces sp. MA37 2'-deoxy-5'-fluoroadenosine + L-methionine
-
 ?
S-(2-amino-6-deaminoadenosyl)-L-methionine + fluoride
-
 Streptomyces sp. MA37 2-amino-5-deamino-5'-deoxy-5'-fluoroadenosine + L-methionine
-
 ?
S-(2-aminoadenosyl)-L-methionine + fluoride
-
 Streptomyces sp. MA37 2-amino-5'-deoxy-5'-fluoroadenosine + L-methionine
-
 ?
S-(2-chloroadenosyl)-L-methionine + fluoride
-
 Streptomyces sp. MA37 2-chloro-5'-deoxy-5'-fluoroadenosine + L-methionine
-
 ?
S-(2-ethynyladenosyl)-L-methionine + fluoride
-
 Streptomyces sp. MA37 2-ethynyl-5'-deoxy-5'-fluoroadenosine + L-methionine
-
 ?