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Literature summary for 2.4.1.40 extracted from
- Effects of plasma glycosyltransferase on the ABO(H) blood group antigens of human von Willebrand factor (2018), Int. J. Hematol., 108, 139-144 .
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | P16442 | - |
- |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | when Von Willebrand factor expressing H-antigen (H-VWF) from blood group O and bovine serum albumin conjugated with H-antigen (H-BSA) are incubated with recombinant alpha1-3-N-acetylgalactosaminyltransferase (rA-transferase) and A-plasma and and UDP-GalNAc, both H-VWF and H-BSA acquire the A-antigen. Incubation with A-plasma very weakly converts the H-antigen on BSA and Von Willebrand factor only in the presence of supplemented UDP-GalNAc. This conversion is enhanced on desialylation of H-VWF | Homo sapiens |
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