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Literature summary for 2.4.1.288 extracted from

  • May, J.F.; Splain, R.A.; Brotschi, C.; Kiessling, L.L.
    A tethering mechanism for length control in a processive carbohydrate polymerization (2009), Proc. Natl. Acad. Sci. USA, 106, 11851-11856.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.4.1.288

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Tuner (DE3) cells Mycobacterium tuberculosis

Organism

Organism UniProt Comment Textmining
Mycobacterium tuberculosis
-
-
-
Mycobacterium tuberculosis H37Rv
-
-
-

Purification (Commentary)

Purification (Comment) Organism
HisTrap column chromatography, gel filtration Mycobacterium tuberculosis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information GlfT2 mediates synthesis of the galactan polymer, which contains between 20 and 40 D-galactofuranose residues connected by alternating beta-D-galactofuranosyl-(1->5)-D-galactofuranose and beta-D-galactofuranosyl-(1->6)-D-galactofuranose linkages. Elongation occurs by addition of D-galactofuranose residues from UDP-alpha-D-galactofuranose to the nonreducing end of a lipid-linked acceptor Mycobacterium tuberculosis ?
-
 ?
additional information no activity with 4-phenoxy-but-2-enyl beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranoside Mycobacterium tuberculosis ?
-
 ?
additional information GlfT2 mediates synthesis of the galactan polymer, which contains between 20 and 40 D-galactofuranose residues connected by alternating beta-D-galactofuranosyl-(1->5)-D-galactofuranose and beta-D-galactofuranosyl-(1->6)-D-galactofuranose linkages. Elongation occurs by addition of D-galactofuranose residues from UDP-alpha-D-galactofuranose to the nonreducing end of a lipid-linked acceptor Mycobacterium tuberculosis H37Rv ?
-
 ?
additional information no activity with 4-phenoxy-but-2-enyl beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranoside Mycobacterium tuberculosis H37Rv ?
-
 ?
UDP-alpha-D-galactofuranose + 12-phenoxy-dodec-2-enyl beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranoside the enzyme functions as a processive polymerase only with 12-phenoxy-dodec-2-enyl beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranoside Mycobacterium tuberculosis UDP + ?
-
 ?
UDP-alpha-D-galactofuranose + 12-phenoxy-dodec-2-enyl beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranoside the enzyme functions as a processive polymerase only with 12-phenoxy-dodec-2-enyl beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranoside Mycobacterium tuberculosis H37Rv UDP + ?
-
 ?
UDP-alpha-D-galactofuranose + 19-phenoxy-nondec-2-enyl beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranoside
-
 Mycobacterium tuberculosis UDP + ?
-
 ?
UDP-alpha-D-galactofuranose + 19-phenoxy-nondec-2-enyl beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranoside
-
 Mycobacterium tuberculosis H37Rv UDP + ?
-
 ?
UDP-alpha-D-galactofuranose + 9-phenoxy-non-2-enyl beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranoside
-
 Mycobacterium tuberculosis UDP + ?
-
 ?
UDP-alpha-D-galactofuranose + 9-phenoxy-non-2-enyl beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranoside
-
 Mycobacterium tuberculosis H37Rv UDP + ?
-
 ?
UDP-alpha-D-galactofuranose + beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
-
 Mycobacterium tuberculosis UDP + [beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)]14-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
-
 ?
UDP-alpha-D-galactofuranose + dec-2-enyl beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranoside
-
 Mycobacterium tuberculosis UDP + ?
-
 ?

Synonyms

Synonyms Comment Organism
galactofuranosyltransferase
-
 Mycobacterium tuberculosis
GlfT2
-
 Mycobacterium tuberculosis
Rv3808c
-
 Mycobacterium tuberculosis